B.Sc. II (Biotechnology) (Semester IV) (CBCS)
Examination, 2018
cytogenetics and population genetics
Day and Date Friday, 7-12-2018 Total Marks 70
Time 10.30 a.m. to 1.00 p.m.
Instructions All questions are compulsory.
Figures to right indicate full marks.
Draw neat and labelled diagrams wherever necessary.
1. Rewrite the following sentences by using correct alternative. 14
Chromosome movement during cell division is brought by
Centromere Chromomere
Centrosome None of these
Facultative Heterochromatin comprise about of genome.
2.5% 3.5% 4.5% 1.5%
Number of Barr bodies present in the nucleus of females is
2 1 3 0
Polytene Chromosome are the permanently chromosome.
Telophase Anaphase
Prophase Metaphase
Aneuploidy was discovered by
Fleming Balbiani Buckert Bridges
Thymine dimmers are caused by
UV rays X rays Alpha rays Beta rays
The number of chromosomes in Pea Plant is
4 23 7 8
Chromonemal Fibrils which can be easily separable from their coil is called
Paranemic Plectonemic
Supercoil Double helix coil
Trisomy of Chromosome 13 results in syndrome.
Down's Edward's
Patau's Klienfelter's
10) Slave genes increase the rate of synthesis.
DNA RNA
Proteins cDNA
11) The "Y" chromosome is placed in of a human karyotype.
Group B Group E Group G Group D
12) Transposons insert themselves at certain positions called
Target Site Parent Site
Hot Spots Direct Repeats
13) Sister chromatids are held together at their centromeres by a protein called
Securin Auxin Cytokinin Cohesion
14) Gametic Meiosis occurs at the time of gametes formation in
Animals and Man Fungi and Algae
Some Algae Some Fungi
2. Solve any seven of the following 14
Define Mutagen.
ii) Define Meiosis.
iii) Define Aneuploidy.
iv) Define Mitotic Index.
Define Gene Frequency.
vi) What are Sex Chromosomes
vii) What are Barr Bodies
viii) What are Microsatellite
ix) What are Insertion Sequences
3. Attempt any two of the following 10
Describe the structure of chromosome with a neat labeled diagram.
Explain in detail types of Mutagenic agents and its effects.
Explain in detail mini-satellite DNA.
Write in detail about the process of Meiosis and add a note on its
significance. 4
4. Attempt any two of the following 14
Write in detail about the numerical changes in chromosome with its application.
Write in detail about the different types of bacterial transposons.
Write in detail about giant chromosomes with neat labeled diagram.
5. Attempt any two of the following 14
Write in detail Hardy-Weinberg law and its application.
Describe multiple factor hypothesis with suitable examples.
Describe the genetic basis of evolution in Brassica and Wheat.