THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LM 361] MAY 2018 Sub. Code: 2922
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH VII PHARMACY PRACTICE
PAPER IV CLINICAL PHARMACY
Q.P. Code 262922
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Write briefly about various pharmacokinetics models. How to determine drug
clearance and volume of distribution in one compartment open model?
2. What are the various phases of clinical trial? Explain about guidelines of good
clinical research practice for clinical trials.
II. Write notes on: (10 x 6 60)
1. Write note on Cardiac markers.
2. Write a note on adverse drug reaction management.
3. Explain plasma protein binding of drugs.
4. Explain patient medication review.
5. Poison management in drug dependence and drug abuse.
6. Dose adjustment in renal failure patients.
7. Write the importance of drug utilization evaluation (DUE).
8. Haematological tests and their significance.
9. How to establish a drug Information centre?
10. Parentral Nutrition.