THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LM 354] MAY 2018 Sub. Code: 2915
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH V PHARMACEUTICAL ANALYSIS
PAPER III ADVANCED PHARMACEUTICAL ANALYSIS
Q.P. Code 262915
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Give the official methods with principle for the determination of:
Androgens Vitamin E Ergot Sulphonamides
2. Explain the procedure and principle involved in the application of following
analytical reagents:
4 Dinitro phenyl hydrazine 2-Naphthoquinone 4-sulphonate
II. Write notes on: (10 x 6 60)
1. Detail about the validation and calibration procedure applied for Infra red
spectrophotometer.
2. Write about the various analytical procedure applied for the estimation of Vit-A.
3. Explain the methods and principle involved in the estimation of ester function.
4. Write about the analytical procedure applied for the estimation of opium
alkaloids.
5. Write detailed note on determination of potassium and calcium.
6. Describe the principle and procedure involved in the LAL'S test.
7. Write the principle and procedure involved in the fluorimeric estimation of
quinine sulphate.
8. Describe the biological assay method for the determination of Rabies vaccine.
9. Write in detailed about bio-availability and bio-equivalence.
10. Add a detailed note for the determination of Penicillin.