M.Sc. (Semester (CBCS) Examination Nov/Dec-2018
Bioinformatics
CELL BIOLOGY AND GENETICS
Time: 2½ Hours Max. Marks: 70
Instructions: All questions are compulsory.
Draw neat and labeled diagrams wherever necessary.
Figures to the right indicate full marks.
Q.1 Rewrite the following sentences by using correct altenative 14
is a cell organelle known as suicide bags of the cell?
Ribosome Lysosome
Peroxisome Mitochondria
is known as programmed cell death.
Apoptosis Endocytosis
Necrosis Metastasis
is responsible for replication of nuclear DNA in eukaryotes.
DNA polymerase DNA polymerase III
DNA polymerase DNA polymerase
In eukaryotic translation process acts as initiator tRNA molecule.
tRNAmet tRNAfmet
tRNAval tRNAleu
In mRNA processing 7-methylguanosine cap is added at the
end of the transcript.
3′ and 5'end 3′ end
2′end 5′ end
During eukaryotic DNA replication process binds directly to
autonomously replicating sequences.
DNA polymerase DNA polymerase III
DNA polymerase Origin recognition complex
Non-coding DNA sequences present in the eukaryotic genes is also known
as
Introns Exons
Coding region Euchromatin
are also known as communicating junctions.
Desmosomes Hemi-Desmosomes
Gap junctions Tight Junctions.
is act as secondary messenger molecule during signal transduction.
Neurotransmitter Enzyme
cAMP Hormones
10) Cdk stands for
Cycline dependent kinases
Caspase dependent kinases
Cytochrome depenent kinases
Cycline degrading kinases
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SLR-VC-48
11) is responsible for acidification of stomach.
Facilitated diffusion Passive transport
Proton pump Simple diffusion
12) enzyme is responsible for protein folding.
Photolyase Photo-reductase
Photo-resolvase Protein disulfide isomerase
13) In operon, responsible for synthesis of inhibitory protein.
Promoter Enhancer
Regulatory gene Operator
14) In BER, responsible for initial recognition of the lesion.
AP endonucleases DNA epinucleaes
DNA Glycosylases DNA exonucleases
Q.2. Answer any four of the following. 08
Enlist functions of RER.
Define Cyclins.
What are exons and introns?
Define operon.
What is RNA editing?
Distinguish between prokaryotic and eukaryotic cell.
Answer the following questions (Any Two) 06
What are gap junctions?
Write note on NPCs.
What is facilitated diffusion?
Q.3. Answer the following. (Any Two) 08
Describe ultra structure and functions of Chloroplast.
Describe signal transduction via G-protein coupled receptors.
Explain process of translation in prokaryotes.
Answer the following:- (Any One) 06
Describe different types of mutations with suitable examples.
Explain process of mitosis with neat labeled diagrams.
Q.4. Answer the following. (Any Two) 10
Describe ultra structure of typical plan cell.
Describe process of apoptosis.
Explain law of independent inheritance with suitable example.
Answer the following:- (Any One) 04
Describe process of DNA replication in bacteria.
Explain regulation of gene expression in lactose operon.
Q.5. Answer the following. (Any Two) 14
Describe mechanisms of D-loop model of DNA replication.
Explain types of active transport with suitable examples.
Explain protein trafficking in mitochondria and endoplasmic reticulum.