M.Sc. (Semester II) (CBCS) Examination Nov/Dec-2018
Biotechnology
CELL BIOLOGY
Time: 2½ Hours Max. Marks: 70
Instructions: All questions of Section I are compulsory.
All questions carry equal marks.
Answer any Four questions from Section II.
Draw neat and labeled diagrams wherever necessary.
SECTION I
Q.1 Rewrite the sentences after choosing the correct answer from the given: 07
Which of the following signals directs a protein to the lysosomes?
A lys-asp-glu-leu (KDEL) sequence in the protein
Attached carbohydrate with terminal mannose-6-phospate
Dolichol phosphate
Attached carbohydrate with terminal mannose
At the end of spermatogenesis each primary spermatocyte gives rise to
Only one spermatid Two spermatids
Four spermatids Three spermatids
In the lancelet, the zygote undergoes cleavage forming a solid ball of cells
of uniform size, called a
Morula Blastula
Gastrula Coelom
Which of the following cytoskeletal structures provides tracks for guiding
intracellular transport?
Intermediate filaments Microtubules
Actin filaments Myosin
Which of the following statements about G proteins is false?
They are involved in signal cascades
They bid to and are regulated by guanine nucleotides
They become activated when bound o GDP
They must be active before the cell can make needed cAMP.
In desmosomes, cadherins link to of an adjacent cell.
Integrins Intermediate filaments
Plasmodesmata Connexons
Just prior to cell division, the diploid human body cell contains
chromatids.
46 23
92 122
Define the terms:- 07
Cell organelles
Kinesin
Cell cycle check points
Ras kinase
Calmodulin
Meiosis
Monospermy
Page 2 of 2
SLR-VE-75
SECTION II
Answer any four of the following:-
Q.2 Explain in detail cascade event of Fertilization and a note on cleavage. 14
Q.3 Explain in detail cell structure and organization of Eukaryotic cell. 14
Q.4 Explain in detail signal transduction by Protein Tyrosine kinase pathway. 14
Q.5 Answer any two from the following: 14
Add a note on Process of Blastulation.
Write a note on 'Microtubular Motor Protein'.
Add a note on Gap Junction.
Q.6 Write short notes on. (Any two) 14
Explain role of Cyclins and Cdks in cell cycle.
Describe cell organelle 'Lysosome'.
Explain role of 'G-protein-Coupled receptor'.