M.Sc. (Semester (CBCS) Examination Nov/Dec-2018
Biotechnology
INHERITANCE BIOLOGY
Time: 2½ Hours Max. Marks: 70
Instructions: All questions are compulsory.
Figures to the right indicate full marks.
Q.1 Multiple choice questions:- 14
Females have a pair of identical sex chromosomes called X chromosomes
hence they are called as
Homomorphic Heteromorphic
Automorphic Gynandromorphic
The ideal DNA markers for genetic mapping and population studies are

Minisatellites Microsatellites
LINES SINES
Gene interaction that involves the masking of the gene effect is

Supplementary Genes Complementary Gene
Epistasis Pleiotropy
The term Organic Evolution was coined by
H. Spencer A.I. Oparin
Aristotle Plato
The production of toxic substance Paramecin is controlled by cytoplasmic
particles called
Kappa particles Alpha particles
Beta particles Delta particles
is a very efficient method of mapping in bacteria.
Transduction Transformation
Conjugation Transfection
is a disease caused due to mutation in mt DNA.
Mycoelonic Epilepsy Bleeder's disease
Down's syndrome None of these
The first human syndrome attributed to chromosomal disorder is
Down's syndrome Turner's Syndrome
Patau's Syndrome Edward's Syndrome
The linkage of the genes in a chromosome is represented in the form of

Genetic Maps Linkage Maps
Chromosome Maps All of these
10) One centimorgan is equal to recombinations.
10%
100% 0.1%
Page 2 of 2
SLR-VE-72
11) Theory of Biogenesis was proposed by
Thales Louis Pasteur
Dobzhansky Oparin
12) The molecular level of transformation was observed by
F. Griffith O. Avery
J. Lederberg L. Tatum
13) A diploid cell missing a single chromosome is
Trisomic Nullisomic
Monosomic Tetrasomic
14) Restricted transduction was first discovered in
Phage P22
T1 phage att
Q.2 Answer the following any four:-
1. Define phenotype
2. Define genetic polymorphism
3. Define C-value paradox
4. Write any two significance of polyploidy
5. Define Hfr.
08
Answer the following any two
1. Law of Co-Dominance with example.
2. Structure of sex chromosome
3. Competency and the factors which effect it.
06
Q.3 Answer the following (Any
1. Explain in detail about lamp brush chromosome with diagram.
2. Explain Griffith's transformation expt with diagram.
3. Write about LINES and its significance.
08
Answer the following (Any
1. Explain the Mendel's Laws of inheritance with examples.
2. Write in details about Hardy Weinberg Law and its significance.
06
Q.4 Answer the following (Any
1. Describe Heterochromatin and Euchromatin.
2. Describe in detail supplementary Gene interaction with example.
3. Write a note on Aneuploidy and disease cause in Man.
10
Answer the following (Any
1. Explain process of linkage with example.
2. Explain Generalized transduction with diagram.
04
Q.5 Answer the following (Any 14
Explain in details about extrachromosomal inheritance in mirabilis jalapa.
Explain in details about ABO Blood group in man and its application.
Explain in detail Darwin's theory of Evolution.