DISTANCE EDUCATION
M.Sc. (Chemistry) DEGREE EXAMINATION, MAY 2018.
ORGANIC CHEMISTRY — II
(2008 onwards)
Time Three hours Maximum 100 marks
Answer any FIVE questions.
All questions carry equal marks.
× 20 100)
1. Write down the schematic analysis of total synhesis of 4 -dimethyl hydroxy pentanoic acid.
Write note on the following reactions:
Periodic acid oxidation
Clemmensen reduction.
Discuss the mechanism of Wagner-Meerwein rearrangement.
2. How would you determine the configuration of
geometrical isomer by physical method?
Explain relay approach with suitable example.
Explain the optical activity of biphenyl.
4. Explain the stability of free radicals.
Discuss elaborately neighbouring group participation with four examples.
Explain the following reactions with suitable example.
Hunsdiecker reaction
Barton reaction.
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5. Give an example for cycloaddition reaction.

Phosphorescence lasts even after the source of light is cut -off-. Explain.
Explain Norrish type I Photochemical reaction with two examples.
Explain the stereo-chemistry of electrocyclic reaction by FMO approach.
6. Explain the various conformation and reactivity of
2-dichloro ethane.
What is the role of free radical in chain reaction?
Discuss elaborately the photo chemical reactions of
Olefins.
7. Explain Barbier-Wieland degradation with an example and mention its use.
How is androsterone prepared from cholesterol?
Give the structure of Vitamin B1 and explain the ring structure present in it.
Give the structure of Vitamin D. What happenswhen it is heated?
8. Elucidate the structure of androsterone.
Discuss the following reactions with suitable example.
Electrocyclic raction
Diel's Alder reaction
Sigmatropic rearrangement.
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