M.Sc. DEGREE EXAMINATION, FEBRUARY 2018.
Fourth semester
Biochemistry
Paper II PROTEOMICS AND GENOMICS
2 1720342
Time 3 Hours Max. Marks 70
PART — A
Answer any six of the following
All questions carry equal marks.
5 30 Marks)
1. Applications of microarry.
2. Genome.
3. Tandem mass spectrometry.
4. Methods of protein in gel digestion.
5. Q-TOF.
6. mi RNA.
7. sh RNA.
8. Gene silencing.
PART — B
Answer all questions.
All questions carry equal marks.
10 40 Marks)
9. Describe Transcriptome and transcriptomics.
Or
Describe the differences between macroarrys and micro arrays.
10. Describe the uses of metabolomics in microbial and plant studies.
Or
Write an account on biological mass spectrometry.
11. Explain the advantages of proteomics over genomics.
Or
Describe the protein annotation based on peptide sequencing.
12. Describe the CRISPER Cas 9 technique in genome editing.
Or
Explain the advantages of CRISPER Cas-9 technology for generating plants
of interest with desired characters.
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