Exam Details
| Subject | drug and medicinal chemistry | |
| Paper | paper 2 | |
| Exam / Course | m.sc. chemistry | |
| Department | ||
| Organization | rayalaseema university | |
| Position | ||
| Exam Date | February, 2018 | |
| City, State | andhra pradesh, kurnool |
Question Paper
M.Sc. DEGREE EXAMINATION, FEBRUARY 2018.
Fourth Semester
Chemistry
Paper II DRUG AND MEDICINAL CHEMISTRY
(Non CBCS Old Regulation)
2 20142
Time 3 Hours Max. Marks 75
SECTION — A
Answer any FIVE questions. 5 25)
1. Explain about neurotransmitters.
2. Write a note on drug targets and receptor theory.
3. Describe Isosteres with example.
4. Write a note on Sulpha drugs.
5. Explain the significance of Lipophilicity.
6. Explain the application of Hammet equation.
7. Explain the role of Lovastatin.
8. Explain about lactam antibiotics.
SECTION — B
Answer ALL questions. 12 2
1 50)
9. Explain about:
Enzyme inhibitors
Agonists with suitable examples.
Or
Describe:
Folkore Drugs
Natural Products as lead structures in Drug discovery with examples.
10. Describe:
Hypnotics
Anti-cancer drugs with examples.
Or
Explain:
Schistosomiasis
Conformational Blockers.
11. Explain about:
QSAR
LFER with examples.
Or
Describe in detail Hansch analysis and significance of slopes and intercepts.
12. Explain in detail about drugs acting on asthma.
Or
Explain in detail about anti-parasitic drugs.
———————
Fourth Semester
Chemistry
Paper II DRUG AND MEDICINAL CHEMISTRY
(Non CBCS Old Regulation)
2 20142
Time 3 Hours Max. Marks 75
SECTION — A
Answer any FIVE questions. 5 25)
1. Explain about neurotransmitters.
2. Write a note on drug targets and receptor theory.
3. Describe Isosteres with example.
4. Write a note on Sulpha drugs.
5. Explain the significance of Lipophilicity.
6. Explain the application of Hammet equation.
7. Explain the role of Lovastatin.
8. Explain about lactam antibiotics.
SECTION — B
Answer ALL questions. 12 2
1 50)
9. Explain about:
Enzyme inhibitors
Agonists with suitable examples.
Or
Describe:
Folkore Drugs
Natural Products as lead structures in Drug discovery with examples.
10. Describe:
Hypnotics
Anti-cancer drugs with examples.
Or
Explain:
Schistosomiasis
Conformational Blockers.
11. Explain about:
QSAR
LFER with examples.
Or
Describe in detail Hansch analysis and significance of slopes and intercepts.
12. Explain in detail about drugs acting on asthma.
Or
Explain in detail about anti-parasitic drugs.
———————
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