M.Sc. DEGREE EXAMINATION, NOVEMBER/DECEMBER 2017.
Third Semester
Chemistry
Paper II MODERN ORGANIC SYNTHESIS

2 20132
Time 3 Hours Max. Marks 75
SECTION — A
Answer any FIVE questions. 5 25 Marks)
Each question carries 5 marks.
1. Explain perkov reactions.
2. Explain HSAB, phosophorous ylides.
3. Explain the protecting of carboxylic acids.
4. Explain Mc. Murrey reaction.
5. Explain about combinatorial synthesis.
6. Explain PTC.
7. Explain FGI.
8. Explain retro synthetic approach.
SECTION — B
Answer ALL questions. 12½ 50 Marks)
9. Explain wittig rearrangement with mechanism.
Or
10. Explain various reactions of sulphur ylides, pummerer rearrangement.
11. Explain Peterson olefination reaction and heck reaction.
Or
12. Explain BINAL and BINAP assisted reactions.

13. Explain Baldwin rules, PTC with examples.
Explain Kahne glycosidation.
Or
14. Explain the rules for determining R/S configeration.
Explain tandem synthesis.
15. Explain Diels alder reaction.
Explain C-C and C-X disconnections.
Or
16. Explain
Michael addition reaction with mechanism.
Regioselectivity with examples.