Explain the following:

Frame-Shift Mutation

Rh-negative individual

Fill in the blanks

is the interaction of non-allelic genes in which one gene masks the expression of another gene.

Hardy-Weinberg equilibrium forms the central theorem of genetics.

Trisomy of chromosome is the cause of Down Syndrome.

Vaccine used against Meningococcal meningitis is purified from Neisseria meningitidis.

Write T for True and F for False for the following statements

Dispermic fertilization is one of the causes of development of sex-mosaics.

A bacteriophage mayor may not have a tail.

Glyphosate is an important plant growth promoter.

Supportive counselling aims at imparting the parents, the knowledge to understand the risks and the probability of their child to have inherited disorders.

Differentiate between the following pairs:

Monozygotic and Dizygotic twins

DNA-denaturation and DNA-renaturation

Represent diagrammatically the life-cycle of a bacteriophage T2.

What is extranuclear inheritance Explain with the help of an example.

Differentiate between the test cross and back-cross.

Explain why the progeny of mulattos ranges from very fair to very dark.

Write short notes on the following:

Recombinant DNA-technique

Griffith's experiment on transformation

Mention the important features of the concept of crossing over.

Explain the following terms

benign tumour; malignant tumour; oncogenesis; metastatis; V-ones.

5. Attempt any two of the following:

Describe the Gibberellic acid-induced transcription in wheat seedling.

Describe the structure of a nucleosome.

With the help of suitable sketches, describe the different forms of chromosome duplications.

What are the characteristics and causes of Huntington's disease?

Describe briefly the contributions of F. Jacob and J. Monod towards our understanding of regulation of gene expression in the prokaryotes.

Explain briefly the XX ZZ XX ploidy-level and compound chromosome systems of sex-determination in animals.