1. Research ethics is to Responsible conduct of research of high ethical standard Educate and monitor the scientists Both of the above None of the above

2. Voluntary participation was initiated in Nuremberg code Helsinki declaration, 1964 Helsinki declaration 2000 None of the above

3. Informed consent indirectly stresses the need of inclusion of literate participants only. True False

4. Informed consent form should contain only the list of names of investigators whom a study participant can contact at any time during the trial. Yes No

5. It is ethical to permit at times the renumeration for the participants. Yes No

6. Informed consent is necessary for the Statistical analysis Purpose of research Validity of test instruments All the above

7. For qualitative studies informed consent form may not be possible. Yes No

8. In ethics deontological approach is Ethical standards are not universal, but are particular to culture and time Comparison of cost and benefit Identification and use of universal code None of the above

9. "Anonymity" means participants' identity is not revealed to others, though the researcher knew the identity. True False

10. Before initiating any form of study procedure the researcher must obtain: A commitment from the participant General information from the participant Informed consent None of the above

11. Choose the odd in ethical issues. Utilitaranism Ethical skepticism Deontology Ontology

12. Desensitizing means a post study interview in which all aspects of the study are revealed, participants questions are answered and reasons for deception if any are given to participants. True False

13. Some amount of deception is permitted to conduct a scientifically valid study. True False

14. The main ethical issues in conducting research in internet platform is Informed consent Privacy Debriefing None of the above

15. Exempt studies are decided Independent Ethics Committee Institutional Review Board Researcher None of the above

16. Any study can be reviewed as "expedited" by Institutional Review Board. True False

17. Under certain conditions waiver of consent form is possible. True False

18. The main drawback of offering financial incentive for participation is Study is more expensive Invite selective bias It is a form of coercive None of the above

19. Plagiarism refers to fabrication of data and results. True False

20. Children's participation presents different problem for researchers than adults because: It is difficult to get informed consent Difficult to analyse children's data There will be more dropouts None of the above

21. Researchers are not given the right of privileged communication offered by law. True False

22. Informed consent: Promotes Clinical Research Offers choice to choose the participant Provides participants' will Provides vital information of the study to trial participant

23. Informed consent should include aim, method and possible conflict of interest. True False

24. Control arm of a clinical trial should be Historical control Best locally available method Best currently available method Any established method

25. According to WHO guidelines, ethical committee should be: Competent Independent Pluralism Transparent

26. Choose the odd in the review process of Institutional Review Board. Express review Expedited review Full review Exempt

27. In a prenatal testing, detection of a faulty gene or a chromosonal abnormality shall provide all the information about the future quality of life or severity of a particular condition. True False

28. Cloning of genes in the laboratory may be the ultimate treatment for genetic disorder. True False

29. First living kidney transplant was performed in 1967 1962 1952 1983

30. A physician who declared that the donor had died can be involved directly for subsequent transplantation. True False

31. Recommended age of an organ donor should be Any age Children Young adults Below 80 years

32. Choose the odd in "Tissue transplantation". Skin Tendons Kidney Heart valves

33. In ethics, device is in vitro agent an instrument a component all of the above

34. A compound formulation made from the components of originally used traditional system should be considered as new substance. True False

35. To evaluate the efficacy of a substance mentioned in the traditional system of medicine, the starting trial phase is Phase I Phase II Phase III Phase IV

36. If predefined parameters in a defined population over a specified period of time are recorded, then it is Cross sectional study Case control study Cohort study All of the above

37. For program evaluation and surveillance in Epidemiology, IEC (Independent Ethics Committee) approval is not necessary. True False

38. If clinical trial is over, and found effective then it is mandatory that the sponsoring agency should provide the drug to the patient till it is marketed. True False

39. For evaluation in India, any new substance discovered abroad need not undergo phase I trial if sufficient information and data are made available. True False

40. If unexpected number of adverse events were found in phase IV study:

(1) The drug should be withdrawn from market immediately The drug should undergo again phase III with more sample size Phase IV continued for some more time None of the above

41. For medical devices the followings are not necessary. Phase I Phase II Phase III All of the above

42. Prevention of pre-conceptual diagnostic technique for pre-selection of sex was introduced in the year (fill) by the Government of India. 1994 2006 2003 None of the above

43. Randomized control trial will not create ethical problem if Placebo is a control Standard drug is a control Trial is open Sample size is large

44. Choose the odd in observational Epidemiology. Cross sectional study Cohort study Case control study Randomized study

45. Genetic test Often does not identify the condition Exactly identifies the risk, but that may not happen in future Exactly identifies the risk that does happen later None of the above

46. Genetic screening and testing need to be accompanied by Counselling and Education. True False

47. Pharmacogenomics aims to Reduce the cost of treatment Understand the differential response to treatment Have Tailor made treatment regimen All of the above

48. Suggested duration of time interval between two trials on the same volunteer will be 3 days 3 months 6 months Same volunteer should not be used again

49. Children born due to failure of contraceptive trials should be Taken care off by the sponsor Followed for any abnormality Keep them in registered orphanages None of the above

50. In human reproduction ART stands for: Artificial Reproductive Technology Assisted Reproductive Technology Artificial Reproductive Therapy Assisted Reproductive Therapy

Write short notes on (200 -300 words) attempt all

51. Observational studies.

52. Major approaches to Ethics.

53. Important considerations for designing an ethical study.

54. Consent form.

55. Genomics.