M.Sc. (Semester (CBCS) Examination Mar/Apr-2018
Biotechnology
CLINICAL BIOINFORMATICS
Time: 2½ Hours
Max. Marks: 70
Instructions: Part Questions 1 is compulsory. Attempt any 4 question from part II. Figures to the right indicate full marks. Answer to the Part I and Part II are to be written in same answer booklet only.
Part I
Q.1

Rewrite the sentence after choosing the correct answer from the given alternatives:
07
R is an language; users typically access it through a command-line interpreter.
Object oriented
Structure oriented
Interpreted
All
CPT is a registered trademark of the Medical Association.
American
Indian
Australian
All of the above
International Statistical Classification of Diseases is developed by
Sanger
WHO
ICHI
ICF
is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger institute.
NCBI
Ensembl
Swiss-Prot
Bio Mart
can be used to filter, reformat, or trim your genomic and metagenomic sequence date.
HTQC
QPLOT
PRINSEQ
FASTX
The first pathogen genome that of was sequenced by traditional Sanger methods
Haemophilus influenza
Staphylococcus epidermidis
Staphylococcus aureus
Neisseria meningitides
FastQC next generation sequencing tool is tool on platform.
Illumina
FASTQ
GNU Glib
CASAVA
Page 2 of 2
SLR-UE-88

Definitions:
07
Epigenomics
Annotation
Neurodegenerative disorders
Clinical trial
Metabolites
Mapviewer
Pathogen
Part II
Answer Any Four of the following:
Q.2
Define NGS. Add a note on its tools and techniques.
14
Q.3
Write a detailed note on pathology informatics with examples.
14
Q.4
Explain the different challenges and applications of pharmacogenomics.
14
Q.5
Answer any two from the following:
14
a)Add a note on Microarray with types.
b)Write a note on medical coding with application.
c)Explain the implication of genome projects in human health disease.
Q.6
Write short notes on any two of following:
14
a)Transcriptomics
b)System Biology
c)Pharmacoviglance