M.Sc. (Semester IV) (CBCS) Examination Mar/Apr-2018
Bioinformatics
EMERGING AREAS OF BIOINFORMATICS
Time: 2½ Hours
Max. Marks: 70
Instructions: Part-1, Question 1 is compulsory Attempt any four questions from Part-II Figures to the right indicate full marks. Answer to the Part-I and Part-II are to be written in same answer Booklet only.
Section I
Q.1

Rewrite the sentence after choosing the correct answer from the given alternatives:
07
are the immunoinformatics tools.
V-Quest
Epimatrix
TAP
All
The size of the nanoparticles are analyzed by
UV
SEM
FTIR
All
SMILES is
Simplified Molecular input line entry system.
Simple Molecular input line entry system.
Simple Molecular index line entry system.
Simplified Molecular index line entry system.
is a federation of database organization access the world.
Catalogue of life
Vplants
TDWG
TIPR
are the descriptors derived from Molecular formula.
1D
3D
2D
0D
Biodiversity informatics was coined by
Ernst Haeckel
John Crenter
John whiting
None
predicts whether an amino acid substitution affects protein function.
Polyphen-2
SIFT
KABAT
IEDB

Definitions:
07
ADMET
LSID
Bucky Ball
Species 2000
SNV
Cancer informatics
QSAR
Page 2 of 2
SLR-UC-77
Section II
Answer any four of the following.
Q.2
What is biodiversity informatics? Explain in detail national, regional and global biodiversity information system and networks?
14
Q.3
Explain chemical file formats in detail? Add a note on SMILES notation.
14
Q.4
Define immunoinformatics? Explain the future of computational modeling prediction in clinical immunology.
14
Q.5
Answer any two of the following.
14
Explain GBIF database in detail.
Synthesis of silver nanoparticles by biological method
Explain chemical structure representation.
Q.6
Write short notes on any two.
14
ChEMBL
Bottom up and top down approach
SIFT and Polyphen-2.