M.Sc. (Semester IV) (CBCS) Examination Mar/Apr-2018
Bioinformatics
CLINICAL BIOINFORMATICS
Time: 2½ Hours
Max. Marks: 70
Instructions: Section Question 1 is compulsory. Attempt any four questions from Section II. Figures to the right indicate full marks. Answers to the Section I and Section II are to be written in same answer booklet only.
Section I
Q.1

Rewrite the sentence after choosing the correct answer from the given alternatives:
07
Malaria is a type of diseases.
Fungal
Bacterial
Virus
Protozoa
is the Next Generation sequencing platforms.
Roche 454
Solexa
SOLiD
All
Bacteremia is
Infection of blood
Infection of body
Infection of lung
Infection of brain
CPT 4 is procedural terminology system.
Current
Clinical
Cytology
All
Human genome project was started in year.
1990
1991
2000
2003
ICD is maintained by
WNO
WHO
UNSECO
Australia
Protein DNA interaction study carried by method.
RNA Seq
ChIp
FAST Q
FAST X

Definitions.
07
FAST Q
Mapviewer
Transcriptomics
Commensalism
Solexa
Ensemble
ADR
Page 2 of 2
SLR-UC-75
Section II
Answer any four of the following.
Q.2
Explain in detail the Neurodegenerative disorders.
14
Q.3
Explain Basic Next generation sequencing chemistry in details and note on microarray data analysis.
14
Q.4
Explain in human Genome Project with its Applications. Add note on Challenges of HGP.
14
Q.5
Answer any two of the following.
14
Explain Medical coding steps in details.
Describe host-pathogen interactions.
Explain transcriptomics in details.
Q.6
Write short notes on any two.
14
Genome sequencing projects
ICD 10
NGS applications