M.Sc. (Semester III) Examination Nov/Dec-2018
Genetics
MEDICAL BIOTECHNOLOGY AND BIONANOTECHNOLOGY
Time: 2½ Hours Max. Marks: 70
Instructions: All questions are compulsory.
Figures to right indicate full marks.
Draw neat and labeled diagrams.
Q.1 Rewrite the following sentences by choosing correct alternatives: 14
gland is present in skin.
Pituitary Lacrimal
Adrenal Sebaceous
Tetanus is caused by
Mycobacterium sp. Vibrio sp.
Klebsiella sp. Clostridium sp.
For the diagnosis of typhoid serological test is used.
VDRL Tri dot
ELISA Widal
Streptomycin inhibits synthesis in bacteria.
Protein Cell wall
Cell membrane DNA
HIV infects cells.
T cell RBCs
Liver cells Neutrophils
For the prevention of Whooping cough, Diptheria and Tetanus
vaccine is used.
BCG DPT
MMR OPV
Attenuation is the process used for preparation of
Antibiotics Enzymes
Vitamins Vaccines
In process of nanoparticle synthesis aqueous solutions at
temperatures above and pressures above 1 atm is used.
Sol process Pyrolysis process
Chemical precipitation process Hydrothermal process
In gene therapy are introduced in the cells to treat disease.
Antibiotics Interferons
Genes Cytokines
10) Sulfonamides inhibit the synthesis of
Riboflavin Folic acid
Pantothenic acid Citric acid
11) Ziehl-Neelsen method is used to stain
Fungi Candida
WBCs Mycobacteria
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SLR-VW-24
12) CD4 count is important in diagnosis of
AIDS Hepatitis
Rabies Swine flu
13) Malaria disease is treated with
Chloroquine phosphate Chloroquine sulphate
Chloroquine nitrate Chloroquine hydrate
14) Physician induced infections resulting from investigative, therapeutic or
other procedures are called infections.
Cross Epidemic
Iatrogenic Subclinical
Q.2 Answer the following (any four) 08
Define infection. Write on infections process.
Give Industrial applications of biosensors.
What is drug resistance? Define MDR.
What are Nanowires and Nanorods? Give examples.
Write on Micelle formation.
Write note on (any two) 06
Normal flora of skin
Laboratory diagnosis of tuberculosis.
New generations of biosensors.
Q.3 Answer the following (any two) 08
Write on Sol and chemical precipitation methods of nanoparticle
synthesis.
Describe Pathogenesis of Tetanus.
Give the mechanism of action of streptomycin antibiotic.
Answer the following (any one) 06
Explain role of nanoparticles in separation of cells and cell Organelles.
Give applications of phages in therapeutics.
Q.4 Answer the following (any two) 10
Describe antifungal drugs with examples.
Explain role of nanotechnology in environmental cleaning and drug
delivery.
Describe Chemical Vapor Deposition and Sputtering.
Answer the following (any one) 04
Write on pathogenesis of candidiasis.
Write on market potential and limitations of biosensors.
Q.5 Answer the following (any two) 14
Discuss cholera with respect to: pathogenesis, lab diagnosis and treatment.
Write on structure, types and mode of action of Sulfonamides and
Polymyxins.
What are vaccines? Write on Subunit, Recombinant and DNA vaccines.